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Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization

Recently, the use of mammalian target of rapamycin (mTOR) inhibitors, in particular rapamycin (Rp), has been suggested to improve the treatment of neurodegenerative diseases. However, as Rp is a strong immunosuppressant, specific delivery to the brain has been postulated to avoid systemic exposure....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nanomaterials (Basel)
Κύριοι συγγραφείς: Polchi, Alice, Magini, Alessandro, Mazuryk, Jarosław, Tancini, Brunella, Gapiński, Jacek, Patkowski, Adam, Giovagnoli, Stefano, Emiliani, Carla
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302501/
https://ncbi.nlm.nih.gov/pubmed/28335215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano6050087
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