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Concurrent measures of fusion and transduction efficiency of primary CD34+ cells with human immunodeficiency virus 1-based lentiviral vectors reveal different effects of transduction enhancers

Lentivirals vectors (LVs) are used for various gene transfer applications, notably for hematopoietic gene therapy, but methods are lacking to precisely evaluate parameters that control the efficiency of transduction in relation with the entry of vectors into target cells. We adapted a fluorescence r...

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Detalles Bibliográficos
Publicado en:Hum Gene Ther Methods
Autores principales: Ingrao, Dina, Majdoul, Saliha, Seye, Ababacar, Galy, Anne, Fenard, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299969/
https://ncbi.nlm.nih.gov/pubmed/24152219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2013.090
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