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Kinetics of lentiviral vector transduction in human CD34(+) cells
Unlike cell lines, human hematopoietic stem cells (HSCs) are less efficiently transduced with HIV-1 vectors, potentially limiting this approach. To investigate which step (internalization, reverse transcription, nuclear transport, and integration) limits lentiviral transduction, we evaluated the kin...
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| 出版年: | Exp Hematol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733401/ https://ncbi.nlm.nih.gov/pubmed/26499040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.10.003 |
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