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Peptides derived from evolutionarily conserved domains in Beclin-1 and Beclin-2 enhance the entry of lentiviral vectors into human cells

Autophagy-related proteins such as Beclin-1 are involved in an array of complex processes, including antiviral responses, and may also modulate the efficiency of gene therapy viral vectors. The Tat-Beclin-1 (TB1) peptide has been reported as an autophagy-inducing factor inhibiting the replication of...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Majdoul, Saliha, Cosette, Jeremie, Seye, Ababacar K., Bernard, Eric, Frin, Sophie, Holic, Nathalie, Chazal, Nathalie, Briant, Laurence, Espert, Lucile, Galy, Anne, Fenard, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682973/
https://ncbi.nlm.nih.gov/pubmed/28928217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.800813
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