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Combination of a Hepatitis C Virus NS3-NS4A Protease Inhibitor and Alpha Interferon Synergistically Inhibits Viral RNA Replication and Facilitates Viral RNA Clearance in Replicon Cells
The present standard of care for hepatitis C virus (HCV) infection is pegylated alpha interferon (IFN-α) in combination with ribavirin. However, specific antivirals such as HCV NS3-NS4A protease inhibitors are now in clinical development, and these agents can potentially be used in combination with...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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American Society for Microbiology
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529208/ https://ncbi.nlm.nih.gov/pubmed/15561857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4784-4792.2004 |
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