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VX-950, a Novel Hepatitis C Virus (HCV) NS3-4A Protease Inhibitor, Exhibits Potent Antiviral Activities in HCV Replicon Cells

The NS3-4A serine protease of hepatitis C virus (HCV) is essential for viral replication and therefore has been one of the most attractive targets for developing specific antiviral agents against HCV. VX-950, a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A prote...

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Autors principals: Lin, Kai, Perni, Robert B., Kwong, Ann D., Lin, Chao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472227/
https://ncbi.nlm.nih.gov/pubmed/16641454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1813-1822.2006
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