Conventional Protein Kinase C Inhibition Prevents Alpha Interferon-Mediated Hepatitis C Virus Replicon Clearance by Impairing STAT Activation

Hepatitis C virus (HCV) has evolved complex strategies to evade host immune responses and establish chronic infection. The only treatment available for HCV infections, alpha interferon (IFN-α), is effective in a limited percentage of patients. The mechanisms by which IFN-α interferes with the HCV li...

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Detalhes bibliográficos
Main Authors: Fimia, Gian Maria, Evangelisti, Cristina, Alonzi, Tonino, Romani, Marta, Fratini, Federica, Paonessa, Giacomo, Ippolito, Giuseppe, Tripodi, Marco, Piacentini, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525020/
https://ncbi.nlm.nih.gov/pubmed/15542633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.12809-12816.2004
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