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Disruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis

Deregulated function of members of the POK (POZ and Krüppel) family of transcriptional repressors, such as promyelocytic leukemia zinc finger (PLZF) and B-cell lymphoma 6 (BCL-6), plays a critical role in the pathogenesis of acute promyelocytic leukemia (APL) and non-Hodgkin's lymphoma, respect...

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Bibliografiske detaljer
Main Authors: Piazza, Francesco, Costoya, José A., Merghoub, Taha, Hobbs, Robin M., Pandolfi, Pier Paolo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC529048/
https://ncbi.nlm.nih.gov/pubmed/15542853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10456-10469.2004
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