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Disruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis

Deregulated function of members of the POK (POZ and Krüppel) family of transcriptional repressors, such as promyelocytic leukemia zinc finger (PLZF) and B-cell lymphoma 6 (BCL-6), plays a critical role in the pathogenesis of acute promyelocytic leukemia (APL) and non-Hodgkin's lymphoma, respect...

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Autori principali: Piazza, Francesco, Costoya, José A., Merghoub, Taha, Hobbs, Robin M., Pandolfi, Pier Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC529048/
https://ncbi.nlm.nih.gov/pubmed/15542853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10456-10469.2004
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