Disruption of Ini1 Leads to Peri-Implantation Lethality and Tumorigenesis in Mice

SNF5/INI1 is a component of the ATP-dependent chromatin remodeling enzyme family SWI/SNF. Germ line mutations of INI1 have been identified in children with brain and renal rhabdoid tumors, indicating that INI1 is a tumor suppressor. Here we report that disruption of Ini1 expression in mice results i...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Guidi, Cynthia J., Sands, Arthur T., Zambrowicz, Brian P., Turner, Tod K., Demers, Delia A., Webster, William, Smith, Thomas W., Imbalzano, Anthony N., Jones, Stephen N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11313485/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.10.3598-3603.2001
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