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Disruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis

Deregulated function of members of the POK (POZ and Krüppel) family of transcriptional repressors, such as promyelocytic leukemia zinc finger (PLZF) and B-cell lymphoma 6 (BCL-6), plays a critical role in the pathogenesis of acute promyelocytic leukemia (APL) and non-Hodgkin's lymphoma, respect...

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Main Authors: Piazza, Francesco, Costoya, José A., Merghoub, Taha, Hobbs, Robin M., Pandolfi, Pier Paolo
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC529048/
https://ncbi.nlm.nih.gov/pubmed/15542853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10456-10469.2004
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