Tdp-43 cryptic exons are highly variable between cell types

BACKGROUND: TDP-43 proteinopathy is a prominent pathological feature that occurs in a number of human diseases including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and inclusion body myositis (IBM). Our recent finding that TDP-43 represses nonconserved cryptic exons led us t...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Jeong, Yun Ha, Ling, Jonathan P., Lin, Sophie Z., Donde, Aneesh N., Braunstein, Kerstin E., Majounie, Elisa, Traynor, Bryan J., LaClair, Katherine D., Lloyd, Thomas E., Wong, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289002/
https://ncbi.nlm.nih.gov/pubmed/28153034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0144-x
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