Tdp-43 cryptic exons are highly variable between cell types

Eitemau Tebyg

• Cryptic Exon Incorporation Occurs in Alzheimer’s Brain lacking TDP-43 Inclusion but Exhibiting Nuclear Clearance of TDP-43
  gan: Sun, Mingkuan, et al.
  Cyhoeddwyd: (2017)
• TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
  gan: Ling, Jonathan P., et al.
  Cyhoeddwyd: (2015)
• Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model
  gan: LaClair, Katherine D., et al.
  Cyhoeddwyd: (2016)
• Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43
  gan: Donde, Aneesh, et al.
  Cyhoeddwyd: (2019)
• Splicing Repression is a Major Function of TDP-43 in Motor Neurons
  gan: Donde, Aneesh, et al.
  Cyhoeddwyd: (2019)