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Splicing Repression is a Major Function of TDP-43 in Motor Neurons
Nuclear depletion of TDP-43, an essential RNA binding protein, may underlie neurodegeneration in amyotrophic lateral sclerosis (ALS). As several functions have been ascribed to this protein, the critical role(s) of TDP-43 in motor neurons that may be compromised in ALS remains unknown. We show here...
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| 出版年: | Acta Neuropathol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6802294/ https://ncbi.nlm.nih.gov/pubmed/31332509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02042-8 |
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