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Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice

TAR DNA-binding protein-43 (TDP-43), a DNA/RNA-binding protein involved in RNA transcription and splicing, has been associated with the pathophysiology of neurodegenerative diseases, including ALS. However, the function of TDP-43 in motor neurons remains undefined. Here we use both gain- and loss-of...

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Главные авторы: Shan, Xiu, Chiang, Po-Min, Price, Donald L., Wong, Philip C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941282/
https://ncbi.nlm.nih.gov/pubmed/20736350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003459107
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