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Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
TAR DNA-binding protein-43 (TDP-43), a DNA/RNA-binding protein involved in RNA transcription and splicing, has been associated with the pathophysiology of neurodegenerative diseases, including ALS. However, the function of TDP-43 in motor neurons remains undefined. Here we use both gain- and loss-of...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941282/ https://ncbi.nlm.nih.gov/pubmed/20736350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003459107 |
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