Wird geladen...

Divergent Phenotypes in Mutant TDP-43 Transgenic Mice Highlight Potential Confounds in TDP-43 Transgenic Modeling

The majority of cases of frontotemporal lobar degeneration and amyotrophic lateral sclerosis are pathologically defined by the cleavage, cytoplasmic redistribution and aggregation of TAR DNA binding protein of 43 kDa (TDP-43). To examine the contribution of these potentially toxic mechanisms in vivo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: D’Alton, Simon, Altshuler, Marcelle, Cannon, Ashley, Dickson, Dennis W., Petrucelli, Leonard, Lewis, Jada
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899264/
https://ncbi.nlm.nih.gov/pubmed/24466128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086513
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!