Divergent Phenotypes in Mutant TDP-43 Transgenic Mice Highlight Potential Confounds in TDP-43 Transgenic Modeling

The majority of cases of frontotemporal lobar degeneration and amyotrophic lateral sclerosis are pathologically defined by the cleavage, cytoplasmic redistribution and aggregation of TAR DNA binding protein of 43 kDa (TDP-43). To examine the contribution of these potentially toxic mechanisms in vivo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: D’Alton, Simon, Altshuler, Marcelle, Cannon, Ashley, Dickson, Dennis W., Petrucelli, Leonard, Lewis, Jada
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899264/
https://ncbi.nlm.nih.gov/pubmed/24466128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086513
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker