Loading...
Studies of alternative isoforms provide insight into TDP-43 autoregulation and pathogenesis
TDP-43 is a soluble, nuclear protein that undergoes cytoplasmic redistribution and aggregation in the majority of cases of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP-43 autoregulates the abundance of its own transcript TARDBP by binding to an intron in the 3′ untranslat...
Na minha lista:
| Udgivet i: | RNA |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509932/ https://ncbi.nlm.nih.gov/pubmed/26089325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047647.114 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|