TDP-43/FUS in Motor Neuron Disease: Complexity and Challenges

Amyotrophic lateral sclerosis (ALS), a common motor neuron disease affecting two per 100,000 people worldwide, encompasses at least five distinct pathological subtypes, including, ALS-SOD1, ALS-C9orf72, ALS-TDP-43, ALS-FUS and Guam-ALS. The etiology of a major subset of ALS involves toxicity of the...

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Publicado en:Prog Neurobiol
Autores principales: Guerrero, Erika N., Wang, Haibo, Mitra, Joy, Hegde, Pavana M., Stowell, Sara E., Liachko, Nicole F, Kraemer, Brian C., Garruto, Ralph M., Rao, K. S., Hegde, Muralidhar L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101148/
https://ncbi.nlm.nih.gov/pubmed/27693252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2016.09.004
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