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A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating, motor neuron degenerative disease without any cure. About 95% of the ALS patients feature abnormalities in the RNA/DNA-binding protein, TDP-43, involving its nucleo-cytoplasmic mislocalization in spinal motor neurons. How TDP-43 pathology trigger...
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| Publicat a: | J Exp Neurosci |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SAGE Publications
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6791036/ https://ncbi.nlm.nih.gov/pubmed/31656396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179069519880166 |
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