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Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime

TAR DNA-binding protein (TDP-43) and fused in sarcoma (FUS) are two highly conserved ribonucleoproteins. Pathogenic mutations of the TDP-43 or the FUS gene are all linked to amyotrophic lateral sclerosis (ALS) that is characterized by progressive degeneration of motor neurons. To better understand t...

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Bibliografiske detaljer
Main Authors: Huang, Cao, Xia, Pedro Yuxing, Zhou, Hongxia
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899457/
https://ncbi.nlm.nih.gov/pubmed/20616880
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