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WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos

Notch signaling in the presomitic mesoderm (psm) is critical for somite formation and patterning. Here, we show that WNT signals regulate transcription of the Notch ligand Dll1 in the tailbud and psm. LEF/TCF factors cooperate with TBX6 to activate transcription from the Dll1 promoter in vitro. Muta...

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書誌詳細
主要な著者: Hofmann, Michael, Schuster-Gossler, Karin, Watabe-Rudolph, Masami, Aulehla, Alexander, Herrmann, Bernhard G., Gossler, Achim
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC528888/
https://ncbi.nlm.nih.gov/pubmed/15545628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1248604
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