WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos

Notch signaling in the presomitic mesoderm (psm) is critical for somite formation and patterning. Here, we show that WNT signals regulate transcription of the Notch ligand Dll1 in the tailbud and psm. LEF/TCF factors cooperate with TBX6 to activate transcription from the Dll1 promoter in vitro. Muta...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Hofmann, Michael, Schuster-Gossler, Karin, Watabe-Rudolph, Masami, Aulehla, Alexander, Herrmann, Bernhard G., Gossler, Achim
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528888/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15545628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1248604
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares