WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos

Notch signaling in the presomitic mesoderm (psm) is critical for somite formation and patterning. Here, we show that WNT signals regulate transcription of the Notch ligand Dll1 in the tailbud and psm. LEF/TCF factors cooperate with TBX6 to activate transcription from the Dll1 promoter in vitro. Muta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hofmann, Michael, Schuster-Gossler, Karin, Watabe-Rudolph, Masami, Aulehla, Alexander, Herrmann, Bernhard G., Gossler, Achim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2004
Pynciau:
Research Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC528888/
https://ncbi.nlm.nih.gov/pubmed/15545628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1248604
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