WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos

Notch signaling in the presomitic mesoderm (psm) is critical for somite formation and patterning. Here, we show that WNT signals regulate transcription of the Notch ligand Dll1 in the tailbud and psm. LEF/TCF factors cooperate with TBX6 to activate transcription from the Dll1 promoter in vitro. Muta...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Hofmann, Michael, Schuster-Gossler, Karin, Watabe-Rudolph, Masami, Aulehla, Alexander, Herrmann, Bernhard G., Gossler, Achim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2004
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528888/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15545628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1248604
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