Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development

BACKGROUND: The evolutionarily conserved Notch signalling pathway regulates multiple developmental processes in a wide variety of organisms. One critical posttranslational modification of Notch for its function in vivo is the addition of O-linked fucose residues by protein O-fucosyltransferase 1 (PO...

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Main Authors: Schuster-Gossler, Karin, Harris, Belinda, Johnson, Kenneth R, Serth, Jürgen, Gossler, Achim
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637848/
https://ncbi.nlm.nih.gov/pubmed/19161597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-6
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