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Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development
BACKGROUND: The evolutionarily conserved Notch signalling pathway regulates multiple developmental processes in a wide variety of organisms. One critical posttranslational modification of Notch for its function in vivo is the addition of O-linked fucose residues by protein O-fucosyltransferase 1 (PO...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637848/ https://ncbi.nlm.nih.gov/pubmed/19161597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-6 |
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