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LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro
The phosphatase Wip1 attenuates the DNA damage response (DDR) by removing phosphorylation marks from a number of DDR proteins (p53, MDM2, Chk1/2, p38). Wip1 also dephosphorylates and inactivates RelA. Notably, LZAP, a putative tumor suppressor, has been linked to dephosphorylation of several of thes...
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| Publicat a: | Cell Cycle |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283812/ https://ncbi.nlm.nih.gov/pubmed/28027003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1261767 |
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