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WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma
The wild-type p53-induced phosphatase 1 (WIP1) is a serine/threonine phosphatase that negatively regulates multiple proteins involved in DNA damage response including p53, CHK2, Histone H2AX, and ATM, and it has been shown to be overexpressed or amplified in human cancers including breast and ovaria...
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| Izdano u: | PLoS One |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319922/ https://ncbi.nlm.nih.gov/pubmed/25658463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115635 |
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