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WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma

The wild-type p53-induced phosphatase 1 (WIP1) is a serine/threonine phosphatase that negatively regulates multiple proteins involved in DNA damage response including p53, CHK2, Histone H2AX, and ATM, and it has been shown to be overexpressed or amplified in human cancers including breast and ovaria...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Richter, Mark, Dayaram, Tajhal, Gilmartin, Aidan G., Ganji, Gopinath, Pemmasani, Sandhya Kiran, Van Der Key, Harjeet, Shohet, Jason M., Donehower, Lawrence A., Kumar, Rakesh
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319922/
https://ncbi.nlm.nih.gov/pubmed/25658463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115635
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