LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro

The phosphatase Wip1 attenuates the DNA damage response (DDR) by removing phosphorylation marks from a number of DDR proteins (p53, MDM2, Chk1/2, p38). Wip1 also dephosphorylates and inactivates RelA. Notably, LZAP, a putative tumor suppressor, has been linked to dephosphorylation of several of thes...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell Cycle
Huvudupphovsmän: Wamsley, J. Jacob, Issaeva, Natalia, An, Hanbing, Lu, Xinyuan, Donehower, Lawrence A., Yarbrough, Wendell G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2016
Ämnen:
Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283812/
https://ncbi.nlm.nih.gov/pubmed/28027003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1261767
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk