Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis

The lungs are ubiquitous receptacles of metastases originating from various bodily tumors. Although osteopontin (SPP1) has been associated with tumor dissemination, the role of its isoforms in lung-directed metastasis is incompletely understood. We employed syngeneic mouse models of spontaneous and...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Giopanou, Ioanna, Lilis, Ioannis, Papaleonidopoulos, Vassilios, Agalioti, Theodora, Kanellakis, Nikolaos I., Spiropoulou, Nikolitsa, Spella, Magda, Stathopoulos, Georgios T.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283628/
https://ncbi.nlm.nih.gov/pubmed/28197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1256528
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