Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis

The lungs are ubiquitous receptacles of metastases originating from various bodily tumors. Although osteopontin (SPP1) has been associated with tumor dissemination, the role of its isoforms in lung-directed metastasis is incompletely understood. We employed syngeneic mouse models of spontaneous and...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Giopanou, Ioanna, Lilis, Ioannis, Papaleonidopoulos, Vassilios, Agalioti, Theodora, Kanellakis, Nikolaos I., Spiropoulou, Nikolitsa, Spella, Magda, Stathopoulos, Georgios T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283628/
https://ncbi.nlm.nih.gov/pubmed/28197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1256528
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