Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis

The lungs are ubiquitous receptacles of metastases originating from various bodily tumors. Although osteopontin (SPP1) has been associated with tumor dissemination, the role of its isoforms in lung-directed metastasis is incompletely understood. We employed syngeneic mouse models of spontaneous and...

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發表在:Oncoimmunology
Main Authors: Giopanou, Ioanna, Lilis, Ioannis, Papaleonidopoulos, Vassilios, Agalioti, Theodora, Kanellakis, Nikolaos I., Spiropoulou, Nikolitsa, Spella, Magda, Stathopoulos, Georgios T.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2016
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283628/
https://ncbi.nlm.nih.gov/pubmed/28197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1256528
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