Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis

The lungs are ubiquitous receptacles of metastases originating from various bodily tumors. Although osteopontin (SPP1) has been associated with tumor dissemination, the role of its isoforms in lung-directed metastasis is incompletely understood. We employed syngeneic mouse models of spontaneous and...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Giopanou, Ioanna, Lilis, Ioannis, Papaleonidopoulos, Vassilios, Agalioti, Theodora, Kanellakis, Nikolaos I., Spiropoulou, Nikolitsa, Spella, Magda, Stathopoulos, Georgios T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283628/
https://ncbi.nlm.nih.gov/pubmed/28197374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1256528
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