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PKM2, cancer metabolism, and the road ahead

A major metabolic aberration associated with cancer is a change in glucose metabolism. Isoform selection of the glycolytic enzyme pyruvate kinase has been implicated in the metabolic phenotype of cancer cells, and specific pyruvate kinase isoforms have been suggested to support divergent energetic a...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Dayton, Talya L, Jacks, Tyler, Vander Heiden, Matthew G
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283597/
https://ncbi.nlm.nih.gov/pubmed/27856534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643300
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