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The importance of serine metabolism in cancer

Serine metabolism is frequently dysregulated in cancers; however, the benefit that this confers to tumors remains controversial. In many cases, extracellular serine alone is sufficient to support cancer cell proliferation, whereas some cancer cells increase serine synthesis from glucose and require...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mattaini, Katherine R., Sullivan, Mark R., Vander Heiden, Matthew G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970329/
https://ncbi.nlm.nih.gov/pubmed/27458133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604085
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