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The importance of serine metabolism in cancer

Serine metabolism is frequently dysregulated in cancers; however, the benefit that this confers to tumors remains controversial. In many cases, extracellular serine alone is sufficient to support cancer cell proliferation, whereas some cancer cells increase serine synthesis from glucose and require...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Mattaini, Katherine R., Sullivan, Mark R., Vander Heiden, Matthew G.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970329/
https://ncbi.nlm.nih.gov/pubmed/27458133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604085
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