PKM2 is not required for pancreatic ductal adenocarcinoma

BACKGROUND: While most cancer cells preferentially express the M2 isoform of the glycolytic enzyme pyruvate kinase (PKM2), PKM2 is dispensable for tumor development in several mouse cancer models. PKM2 is expressed in human pancreatic cancer, and there have been conflicting reports on the associatio...

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Foilsithe in:Cancer Metab
Main Authors: Hillis, Alissandra L, Lau, Allison N, Devoe, Camille X, Dayton, Talya L, Danai, Laura V, Di Vizio, Dolores, Vander Heiden, Matthew G
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Short Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198443/
https://ncbi.nlm.nih.gov/pubmed/30386596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-018-0188-1
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