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Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug
A scalable and versatile approach is reported to prepare high paclitaxel (PTX)-loading and low-systemic-toxicity nanoparticles via one-step ring-opening polymerization of a prodrug monomer consisting of PTX that is appended to a cyclic carbonate through a hydrolysable ester linker. Initiating this m...
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| Опубликовано в: : | Adv Healthc Mater |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5279999/ https://ncbi.nlm.nih.gov/pubmed/27111757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201600230 |
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