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A modular method for high yield synthesis of site-specific protein–polymer therapeutics

A new and versatile method is described to engineer precisely defined protein/peptide–polymer therapeutics by a modular approach that consists of three steps: (1) fuse a protein/peptide of interest with an elastin–like–polypeptide that enables facile purification and high yield; followed by (2) inst...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Pang, Yan, Liu, Jinyao, Qi, Yizhi, Li, Xinghai, Chilkoti, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320947/
https://ncbi.nlm.nih.gov/pubmed/27439953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201604661
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