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SITE-SPECIFIC AND STOICHIOMETRIC STEALTH POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEINS

As potent and selective therapeutic agents, peptides and proteins are an important class of drugs, but they typically have sub-optimal pharmacokinetic profiles. One approach to solve this problem is by their conjugation with “stealth” polymers. Conventional methods for conjugation of this class of p...

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Publicat a:Bioconjug Chem
Autors principals: Ozer, Imran, Chilkoti, Ashutosh
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372107/
https://ncbi.nlm.nih.gov/pubmed/27998056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00652
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