Switchable elastin-like polypeptides that respond to chemical inducers of dimerization

Por Dhandhukia, Jugal, Weitzhandler, Isaac, Wang, Wan, MacKay, J. Andrew
Publicado em 2013

Micellar self-assembly of perfectly sequence-defined recombinant resilin-like/elastin-like block copolypeptides

Por Weitzhandler, Isaac, Dzuricky, Michael, Hoffmann, Ingo, Quiroz, Felipe Garcia, Gradzielski, Michael, Chilkoti, Ashutosh
Publicado no Biomacromolecules (2017)

Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug

Por Liu, Jinyao, Pang, Yan, Bhattacharyya, Jayanta, Liu, Wenge, Weitzhandler, Isaac, Li, Xinghai, Chilkoti, Ashutosh
Publicado no Adv Healthc Mater (2016)

Phase behavior and self-assembly of perfectly sequence-defined and monodisperse multi-block copolypeptides

Por MacEwan, Sarah R., Weitzhandler, Isaac, Hoffmann, Ingo, Genzer, Jan, Gradzielski, Michael, Chilkoti, Ashutosh
Publicado no Biomacromolecules (2017)

A tunable and reversible platform for the intracellular formation of genetically engineered protein microdomains

Por Pastuszka, Martha K., Janib, Siti M., Weitzhandler, Isaac, Okamoto, Curtis T., Hamm-Alvarez, Sarah, MacKay, J. Andrew
Publicado em 2012

Inducible Fibril Formation of Silk–Elastin Diblocks

Por Willems, Lione, Roberts, Stefan, Weitzhandler, Isaac, Chilkoti, Ashutosh, Mastrobattista, Enrico, van der Oost, John, de Vries, Renko
Publicado no ACS Omega (2019)

Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug Loaded Nanoparticles**

Por Liu, Jinyao, Liu, Wenge, Weitzhandler, Isaac, Bhattacharyya, Jayanta, Li, Xinghai, Wang, Jing, Qi, Yizhi, Bhattacharjee, Somnath, Chilkoti, Ashutosh
Publicado no Angew Chem Int Ed Engl (2014)

Intrinsically disordered proteins access a range of hysteretic phase separation behaviors

Por Garcia Quiroz, Felipe, Li, Nan K., Roberts, Stefan, Weber, Patrick, Dzuricky, Michael, Weitzhandler, Isaac, Yingling, Yaroslava G., Chilkoti, Ashutosh
Publicado no Sci Adv (2019)

Noncanonical Self-Assembly of Highly Asymmetric Genetically Encoded Polypeptide Amphiphiles into Cylindrical Micelles

Por McDaniel, Jonathan R., Weitzhandler, Isaac, Prevost, Sylvain, Vargo, Kevin B., Appavou, Marie-Sousai, Hammer, Daniel A., Gradzielski, Michael, Chilkoti, Ashutosh
Publicado no Nano Lett (2014)

Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy

Por Bhattacharyya, Jayanta, Weitzhandler, Isaac, Ho, Shihan Bryan, McDaniel, Jonathan R., Li, Xinghai, Tang, Lei, Liu, Jinyao, Dewhirst, Mark, Chilkoti, Ashutosh
Publicado no Adv Funct Mater (2017)

Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation

Por Bhattacharjee, Somnath, Liu, Wenge, Wang, Wei-Han, Weitzhandler, Isaac, Li, Xinghai, Qi, Yizhi, Liu, Jinyao, Pang, Yan, Hunt, Donald F., Chilkoti, Ashutosh
Publicado no Chembiochem (2015)

A Paclitaxel-Loaded Recombinant Polypeptide Nanoparticle Outperforms Abraxane in Multiple Murine Cancer Models

Por Bhattacharyya, Jayanta, Bellucci, Joseph J., Weitzhandler, Isaac, McDaniel, Jonathan R., Spasojevic, Ivan, Li, Xinghai, Lin, Chao-Chieh, Chi, Jen-Tsan Ashley, Chilkoti, Ashutosh
Publicado no Nat Commun (2015)

Nature of Amorphous Hydrophilic Block Affects Self-Assembly of an Artificial Viral Coat Polypeptide

Por Willems, Lione, van Westerveld, Larissa, Roberts, Stefan, Weitzhandler, Isaac, Calcines Cruz, Carlos, Hernandez-Garcia, Armando, Chilkoti, Ashutosh, Mastrobattista, Enrico, van der Oost, John, de Vries, Renko
Publicado no Biomacromolecules (2019)

Genetically encoded lipid–polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly

Por Mozhdehi, Davoud, Luginbuhl, Kelli M., Simon, Joseph R., Dzuricky, Michael, Berger, Rüdiger, Varol, H. Samet, Huang, Fred C., Buehne, Kristen L., Mayne, Nicholas R., Weitzhandler, Isaac, Bonn, Mischa, Parekh, Sapun H., Chilkoti, Ashutosh
Publicado no Nat Chem (2018)