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Switchable elastin-like polypeptides that respond to chemical inducers of dimerization

Elastin-like polypeptides (ELPs) are protein polymers that reversibly phase separate in response to increased temperature, pressure, concentration, ionic strength, and molecular weight. If it were possible to engineer their phase separation to respond to specific molecular substrates, ELP fusion pro...

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Detalhes bibliográficos
Main Authors: Dhandhukia, Jugal, Weitzhandler, Isaac, Wang, Wan, MacKay, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721738/
https://ncbi.nlm.nih.gov/pubmed/23406497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301558q
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