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Switchable elastin-like polypeptides that respond to chemical inducers of dimerization

Elastin-like polypeptides (ELPs) are protein polymers that reversibly phase separate in response to increased temperature, pressure, concentration, ionic strength, and molecular weight. If it were possible to engineer their phase separation to respond to specific molecular substrates, ELP fusion pro...

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Detalles Bibliográficos
Main Authors: Dhandhukia, Jugal, Weitzhandler, Isaac, Wang, Wan, MacKay, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721738/
https://ncbi.nlm.nih.gov/pubmed/23406497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301558q
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