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Scalable Synthesis of (−)-Thapsigargin
[Image: see text] Total syntheses of the complex, highly oxygenated sesquiterpenes thapsigargin (1) and nortrilobolide (2) are presented. Access to analogues of these promising bioactive natural products has been limited to tedious isolation and semisynthetic efforts. Elegant prior total syntheses d...
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| Veröffentlicht in: | ACS Cent Sci |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2016
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5269647/ https://ncbi.nlm.nih.gov/pubmed/28149952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00313 |
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