Synthesis of the thapsigargins

The thapsigargins are a family of complex guaianolides with potent and selective Ca(2+)-modulating properties. This article documents the evolution of a synthetic route through several iterations to a final practical and scaleable synthetic route capable of generating both unnatural and natural prod...

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Detalhes bibliográficos
Main Authors: Ley, Steven V., Antonello, Alessandra, Balskus, Emily P., Booth, David T., Christensen, Søren B., Cleator, Ed, Gold, Helen, Högenauer, Klemens, Hünger, Udo, Myers, Rebecca M., Oliver, Steven F., Simic, Oliver, Smith, Martin D., Søhoel, Helmer, Woolford, Alison J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Natural Product Synthesis Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514437/
https://ncbi.nlm.nih.gov/pubmed/15226504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403300101
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