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Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

Since cells in solid tumors divide less rapidly than cells in the bone marrow or cells of the immune system, mitotic inhibitors often cause severe side effects when used for treatment of diseases like prostate cancer and breast cancer. One approach to overcome this problem involves attempts at devel...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zimmermann, Tomas, Christensen, Søren Brøgger, Franzyk, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100299/
https://ncbi.nlm.nih.gov/pubmed/29914143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061463
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