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Scalable Synthesis of (−)-Thapsigargin
[Image: see text] Total syntheses of the complex, highly oxygenated sesquiterpenes thapsigargin (1) and nortrilobolide (2) are presented. Access to analogues of these promising bioactive natural products has been limited to tedious isolation and semisynthetic efforts. Elegant prior total syntheses d...
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| Publicado no: | ACS Cent Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2016
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5269647/ https://ncbi.nlm.nih.gov/pubmed/28149952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00313 |
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