GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal

G protein-coupled receptor kinases (GRKs) are critically involved in immune response through regulation of cytokine receptors in mature leukocytes, but their role in hematopoiesis is largely unknown. Here, we demonstrate that GRK6 knockout (GRK6(−/−)) mice exhibit lymphocytopenia, loss of the hemato...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Le, Qiumin, Yao, Wenqing, Chen, Yuejun, Yan, Biao, Liu, Cao, Yuan, Man, Zhou, Yuqing, Ma, Lan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260904/
https://ncbi.nlm.nih.gov/pubmed/27882944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.377
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares