GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal

G protein-coupled receptor kinases (GRKs) are critically involved in immune response through regulation of cytokine receptors in mature leukocytes, but their role in hematopoiesis is largely unknown. Here, we demonstrate that GRK6 knockout (GRK6(−/−)) mice exhibit lymphocytopenia, loss of the hemato...

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Foilsithe in:Cell Death Dis
Main Authors: Le, Qiumin, Yao, Wenqing, Chen, Yuejun, Yan, Biao, Liu, Cao, Yuan, Man, Zhou, Yuqing, Ma, Lan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260904/
https://ncbi.nlm.nih.gov/pubmed/27882944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.377
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