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GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal
G protein-coupled receptor kinases (GRKs) are critically involved in immune response through regulation of cytokine receptors in mature leukocytes, but their role in hematopoiesis is largely unknown. Here, we demonstrate that GRK6 knockout (GRK6(−/−)) mice exhibit lymphocytopenia, loss of the hemato...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5260904/ https://ncbi.nlm.nih.gov/pubmed/27882944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.377 |
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