Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity for self-renewal to maintain the HSCs’ pool and the ability for multilineage differentiation, which are responsible for sustained production of multiple blood lineages. The regulation of HSC development is controlled precisely by complex signal netwo...

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Veröffentlicht in:FASEB J
Hauptverfasser: Liu, Juanjuan, Cui, Zhengzhi, Wang, Fang, Yao, Yingpeng, Yu, Guotao, Liu, Jingjing, Cao, Dengchao, Niu, Shuaishuai, You, Menghao, Sun, Zhen, Lian, Di, Zhao, Tianyan, Kang, Youmin, Zhao, Yaofeng, Xue, Hai-Hui, Yu, Shuyang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988868/
https://ncbi.nlm.nih.gov/pubmed/30668923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802072R
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