METTL3-dependent m(6)A modification programs T follicular helper cell differentiation

T follicular helper (T(FH)) cells are specialized effector CD4(+) T cells critical to humoral immunity. Whether post-transcriptional regulation has a function in T(FH) cells is unknown. Here, we show conditional deletion of METTL3 (a methyltransferase catalyzing mRNA N(6)-methyladenosine (m(6)A) mod...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yao, Yingpeng, Yang, Ying, Guo, Wenhui, Xu, Lifan, You, Menghao, Zhang, Yi-Chang, Sun, Zhen, Cui, Xiao, Yu, Guotao, Qi, Zhihong, Liu, Jingjing, Wang, Fang, Liu, Juanjuan, Zhao, Tianyan, Ye, Lilin, Yang, Yun-Gui, Yu, Shuyang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910450/
https://ncbi.nlm.nih.gov/pubmed/33637761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21594-6
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