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The kinase PDK1 is critical for promoting T follicular helper cell differentiation
The kinase PDK1 is a crucial regulator for immune cell development by connecting PI3K to downstream AKT signaling. However, the roles of PDK1 in CD4(+) T cell differentiation, especially in T follicular helper (Tfh) cell, remain obscure. Here we reported PDK1 intrinsically promotes the Tfh cell diff...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7889074/ https://ncbi.nlm.nih.gov/pubmed/33595435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61406 |
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