SRSF1 serves as a critical posttranscriptional regulator at the late stage of thymocyte development

The underlying mechanisms of thymocyte maturation remain largely unknown. Here, we report that serine/arginine-rich splicing factor 1 (SRSF1) intrinsically regulates the late stage of thymocyte development. Conditional deletion of SRSF1 resulted in severe defects in maintenance of late thymocyte sur...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Qi, Zhihong, Wang, Fang, Yu, Guotao, Wang, Di, Yao, Yingpeng, You, Menghao, Liu, Jingjing, Liu, Juanjuan, Sun, Zhen, Ji, Ce, Xue, Yuanchao, Yu, Shuyang
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051871/
https://ncbi.nlm.nih.gov/pubmed/33863728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf0753
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